Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis.

The p53 tumor suppressor protein is a sequence-specific transcriptional activator of target genes. Exposure of cells to DNA damage results in accumulation of biochemically active p53, with consequent activation of p53-responsive promoters. In order to study how the transcriptional activity of the p5...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Gottlieb, E, Haffner, R, King, A, Asher, G, Gruss, P, Lonai, P, Oren, M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169735/
https://ncbi.nlm.nih.gov/pubmed/9135153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.6.1381
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