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The proteolytic cleavage of eukaryotic initiation factor (eIF) 4G is prevented by eIF4E binding protein (PHAS-I; 4E-BP1) in the reticulocyte lysate.

A common feature of viral infection is the subversion of the host cell machinery towards the preferential translation of viral products. In some instances, this is partly mediated by the expression of virally encoded proteases which lead to the cleavage of initiation factor eIF4G. The foot-and-mouth...

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Hlavní autoři: Ohlmann, T, Pain, V M, Wood, W, Rau, M, Morley, S J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169685/
https://ncbi.nlm.nih.gov/pubmed/9049313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.4.844
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