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Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation.

Small heat shock proteins (sHsps) are a conserved and ubiquitous protein family. Their ability to convey thermoresistance suggests their participation in protecting the native conformation of proteins. However, the underlying functional principles of their protective properties and their role in con...

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Détails bibliographiques
Auteurs principaux: Ehrnsperger, M, Gräber, S, Gaestel, M, Buchner, J
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169629/
https://ncbi.nlm.nih.gov/pubmed/9029143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.2.221
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