Cardiac Tissue-Specific Repression of CELF Activity Disrupts Alternative Splicing and Causes Cardiomyopathy

Eitemau Tebyg

• The CELF Family of RNA Binding Proteins Is Implicated in Cell-Specific and Developmentally Regulated Alternative Splicing
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  Cyhoeddwyd: (2001)
• Repression of nuclear CELF activity can rescue CELF-regulated alternative splicing defects in skeletal muscle models of myotonic dystrophy
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  Cyhoeddwyd: (2012)
• Identification of CELF splicing activation and repression domains in vivo
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  Cyhoeddwyd: (2005)
• RNA binding protein 24 deletion disrupts global alternative splicing and causes dilated cardiomyopathy
  gan: Liu, Jing, et al.
  Cyhoeddwyd: (2018)
• Nucleotide substitutions within the cardiac troponin T alternative exon disrupt pre-mRNA alternative splicing.
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  Cyhoeddwyd: (1989)