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Regulation of mTOR and Cell Growth in Response to Energy Stress by REDD1

The tuberous sclerosis tumor suppressors TSC1 and TSC2 regulate the mTOR pathway to control translation and cell growth in response to nutrient and growth factor stimuli. We have recently identified the stress response REDD1 gene as a mediator of tuberous sclerosis complex (TSC)-dependent mTOR regul...

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Bibliografiske detaljer
Main Authors: Sofer, Avi, Lei, Kui, Johannessen, Cory M., Ellisen, Leif W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168803/
https://ncbi.nlm.nih.gov/pubmed/15988001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.14.5834-5845.2005
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