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Antimicrobial and Chemoattractant Activity, Lipopolysaccharide Neutralization, Cytotoxicity, and Inhibition by Serum of Analogs of Human Cathelicidin LL-37

Antimicrobial peptides have been evaluated in vitro and in vivo as alternatives to conventional antibiotics. Apart from being antimicrobial, the native human cathelicidin-derived peptide LL-37 (amino acids [aa] 104 to 140 of the human cathelicidin antimicrobial peptide) also binds and neutralizes ba...

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Autors principals: Ciornei, Cristina D., Sigurdardóttir, Thorgerdur, Schmidtchen, Artur, Bodelsson, Mikael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168709/
https://ncbi.nlm.nih.gov/pubmed/15980359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2845-2850.2005
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