Augmentation of the Lipopolysaccharide-Neutralizing Activities of Human Cathelicidin CAP18/LL-37-Derived Antimicrobial Peptides by Replacement with Hydrophobic and Cationic Amino Acid Residues

Mammalian myeloid and epithelial cells express various peptide antibiotics (such as defensins and cathelicidins) that contribute to the innate host defense against invading microorganisms. Among these peptides, human cathelicidin CAP18/LL-37 (L(1) to S(37)) possesses not only potent antibacterial ac...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Nagaoka, Isao, Hirota, Satoko, Niyonsaba, François, Hirata, Michimasa, Adachi, Yoshiyuki, Tamura, Hiroshi, Tanaka, Shigenori, Heumann, Didier
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Microbial Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC120071/
https://ncbi.nlm.nih.gov/pubmed/12204946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.9.5.972-982.2002
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge