Reduced Susceptibility of Staphylococcus aureus to Vancomycin and Platelet Microbicidal Protein Correlates with Defective Autolysis and Loss of Accessory Gene Regulator (agr) Function

Loss of agr function, vancomycin exposure, and abnormal autolysis have been linked with both development of the GISA phenotype and low-level resistance in vitro to thrombin-induced platelet microbicidal proteins (tPMPs). We examined the potential in vitro interrelationships among these parameters in...

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Detalhes bibliográficos
Main Authors: Sakoulas, George, Eliopoulos, George M., Fowler, Vance G., Moellering, Robert C., Novick, Richard P., Lucindo, Natalie, Yeaman, Michael R., Bayer, Arnold S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168700/
https://ncbi.nlm.nih.gov/pubmed/15980337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2687-2692.2005
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