Reduced Susceptibility of Staphylococcus aureus to Vancomycin and Platelet Microbicidal Protein Correlates with Defective Autolysis and Loss of Accessory Gene Regulator (agr) Function

Loss of agr function, vancomycin exposure, and abnormal autolysis have been linked with both development of the GISA phenotype and low-level resistance in vitro to thrombin-induced platelet microbicidal proteins (tPMPs). We examined the potential in vitro interrelationships among these parameters in...

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Hlavní autoři: Sakoulas, George, Eliopoulos, George M., Fowler, Vance G., Moellering, Robert C., Novick, Richard P., Lucindo, Natalie, Yeaman, Michael R., Bayer, Arnold S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168700/
https://ncbi.nlm.nih.gov/pubmed/15980337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2687-2692.2005
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