Emergence of a Novel Mutation in the FLLA Region of Hepatitis B Virus during Lamivudine Therapy

The emergence of resistance to lamivudine has been one of the major stumbling blocks to successful treatment and control of hepatitis B virus (HBV) infections. The major mechanism of resistance has been attributed to the alteration in the YMDD motif of the HBV polymerase due to an amino acid change...

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Hlavní autoři: Pai, S. Balakrishna, Bozdayi, A. Mithat, Pai, Rekha B., Beker, Tolunay, Sarioglu, Mustafa, Turkyilmaz, Ahmet R., Grier, Jason, Yurdaydin, Cihan, Schinazi, Raymond F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168680/
https://ncbi.nlm.nih.gov/pubmed/15980328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2618-2624.2005
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