Genetic Approach To Study the Relationship between Penicillin-Binding Protein 3 Mutations and Haemophilus influenzae β-Lactam Resistance by Using Site-Directed Mutagenesis and Gene Recombinants

To clarify the relationship between mutations commonly found for penicillin-binding protein 3 (PBP 3) of β-lactamase-nonproducing ampicillin-resistant (BLNAR) Haemophilus influenzae isolates and β-lactam resistance, single and multiple amino acid mutations at positions 377, 385, 389, 517, and 526 we...

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Detalhes bibliográficos
Main Authors: Osaki, Yumi, Sanbongi, Yumiko, Ishikawa, Midori, Kataoka, Hiroshi, Suzuki, Takahisa, Maeda, Kumiko, Ida, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168665/
https://ncbi.nlm.nih.gov/pubmed/15980357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2834-2839.2005
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