Amino Acid Substitutions in Mosaic Penicillin-Binding Protein 2 Associated with Reduced Susceptibility to Cefixime in Clinical Isolates of Neisseria gonorrhoeae

The molecular mechanisms of reduced susceptibility to cefixime in clinical isolates of Neisseria gonorrhoeae, particularly amino acid substitutions in mosaic penicillin-binding protein 2 (PBP2), were examined. The complete sequence of ponA, penA, and por genes, encoding, respectively, PBP1, PBP2, an...

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Hlavní autoři: Takahata, Sho, Senju, Nami, Osaki, Yumi, Yoshida, Takuji, Ida, Takashi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635225/
https://ncbi.nlm.nih.gov/pubmed/16940068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00626-06
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