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Time-Kill Study of the Activity of Telithromycin against Macrolide-Resistant Streptococcus pneumoniae Isolates with 23S rRNA Mutations and Changes in Ribosomal Proteins L4 and L22

By use of a time-kill methodology, the antipneumococcal activity of telithromycin was determined against macrolide-resistant S. pneumoniae isolates having mutations in the 23S rRNA gene and changes in the ribosomal proteins L4 and L22. Telithromycin had MICs ranging between 0.03 and 0.25 μg/ml and w...

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Bibliografische gegevens
Hoofdauteurs: Reinert, Ralf René, Al-Lahham, Adnan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168645/
https://ncbi.nlm.nih.gov/pubmed/15980387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.3011-3013.2005
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