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Time-Kill Study of the Activity of Telithromycin against Macrolide-Resistant Streptococcus pneumoniae Isolates with 23S rRNA Mutations and Changes in Ribosomal Proteins L4 and L22
By use of a time-kill methodology, the antipneumococcal activity of telithromycin was determined against macrolide-resistant S. pneumoniae isolates having mutations in the 23S rRNA gene and changes in the ribosomal proteins L4 and L22. Telithromycin had MICs ranging between 0.03 and 0.25 μg/ml and w...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2005
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1168645/ https://ncbi.nlm.nih.gov/pubmed/15980387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.3011-3013.2005 |
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