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Structural Diversity of Streptokinase and Activation of Human Plasminogen
The β domain of streptokinase is required for plasminogen activation and contains a region of sequence diversity associated with infection and disease in group A streptococci. We report that mutagenesis of this polymorphic region does not alter plasminogen activation, which suggests an alternative f...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1168554/ https://ncbi.nlm.nih.gov/pubmed/15972548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.7.4451-4453.2005 |
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