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Phosphatidylinositol cleavage in lymphocytes. Requirement for calcium ions at a low concentration and effects of other cations
The soluble activity in lymphocytes which converts phosphatidylinositol into 1,2-diacylglycerol and inositol phosphates requires Ca(2+) ions. At pH7 maximum activity occurs at [Ca(2+)](free) ≈ 0.7μm whereas at pH5.5 the equivalent value is approx. 50μm. At [Ca(2+)](free) ≈ 1μm, a concentration simil...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1974
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1168324/ https://ncbi.nlm.nih.gov/pubmed/4377211 |
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