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Phosphatidylinositol cleavage in lymphocytes. Requirement for calcium ions at a low concentration and effects of other cations

The soluble activity in lymphocytes which converts phosphatidylinositol into 1,2-diacylglycerol and inositol phosphates requires Ca(2+) ions. At pH7 maximum activity occurs at [Ca(2+)](free) ≈ 0.7μm whereas at pH5.5 the equivalent value is approx. 50μm. At [Ca(2+)](free) ≈ 1μm, a concentration simil...

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Detalhes bibliográficos
Main Authors: Allan, David, Michell, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168324/
https://ncbi.nlm.nih.gov/pubmed/4377211
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