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Methyltransferase inhibitors block NGF-regulated survival and protein phosphorylation in sympathetic neurons.

Nerve growth factor (NGF) and elevated K+ concentrations (35 mM) support the survival of the same population of chick embryonic sympathetic neurons. We have used methyltransferase inhibitors, which block protein methylation in intact cells, to investigate the mechanism(s) by which NGF and high K+ ex...

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Bibliographic Details
Main Authors: Acheson, A, Vogl, W, Huttner, W B, Thoenen, H
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1167225/
https://ncbi.nlm.nih.gov/pubmed/3792300
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