Growth factors induce early pre-replicative changes in senescent human fibroblasts.

As human fibroblasts in culture senesce their response to platelet-derived growth factor (PDGF) becomes attenuated. To clarify at which level such cells are blocked in the pre-replicative part of the cell cycle, we have analysed PDGF-induced pre-replicative events in senescent (phase III) cultures....

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Detalhes bibliográficos
Main Authors: Paulsson, Y, Bywater, M, Pfeifer-Ohlsson, S, Ohlsson, R, Nilsson, S, Heldin, C H, Westermark, B, Betsholtz, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1167095/
https://ncbi.nlm.nih.gov/pubmed/3023058
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