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Secretion in yeast: translocation and glycosylation of prepro-α-factor in vitro can occur via an ATP-dependent post-translational mechanism

In an in vitro system comprising a yeast cell-free translation system, yeast microsomes and mRNA encoding prepro-α-factor, the translocation of this protein across the membrane of the microsomal vesicle and its glycosylation could be uncoupled from its translation. Such post-translational processing...

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Bibliographic Details
Main Authors: Rothblatt, Jonathan A., Meyer, David I.
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166897/
https://ncbi.nlm.nih.gov/pubmed/15957217
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