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Expression of a mutant vasopressin gene: differential polyadenylation and read-through of the mRNA 3' end in a frame-shift mutant.

Sequence analysis of cDNA clones derived from hypothalamic mRNA of diabetes insipidus (Brattleboro) rats shows that the vasopressin gene transcript also includes the single base deletion demonstrated in the gene. This causes a frame-shift in the C terminus of the vasopressin precursor with a reading...

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Main Authors: Ivell, R, Schmale, H, Krisch, B, Nahke, P, Richter, D
格式: Artigo
語言:Inglês
出版: 1986
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166890/
https://ncbi.nlm.nih.gov/pubmed/3755103
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