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α(1)-Adrenoceptor stimulation potentiates L-type Ca(2+) current through Ca(2+)/calmodulin-dependent PK II (CaMKII) activation in rat ventricular myocytes
α(1)-Adrenoceptor stimulation (α(1)ARS) modulates cardiac muscle contraction under physiological conditions by means of changes in Ca(2+) current through L-type channels (I(Ca,L)) and Ca(2+) ensitivity of the myofilaments. However, the cellular mechanisms of α(1)ARS are not fully clarified. In this...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1166620/ https://ncbi.nlm.nih.gov/pubmed/15964981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503569102 |
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