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Potential genetic modifiers of the cystic fibrosis intestinal inflammatory phenotype on mouse chromosomes 1, 9, and 10

BACKGROUND: Although cystic fibrosis is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the severity of disease is highly variable indicating the influence of modifier genes. The intestines of Cftr deficient mice (CF mice: Cftr(tm1Unc)) are prone to obstru...

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Autori principali: Norkina, Oxana, De Lisle, Robert C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166548/
https://ncbi.nlm.nih.gov/pubmed/15921521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-29
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