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Affinity labelling of the binding site of rabbit antibody. Evidence for the involvement of the hypervariable regions of the heavy chain

The binding sites of rabbit antibodies with affinity for the haptenic group 4-azido-2-nitrophenyl-lysine have been specifically labelled by photolysis of the hapten–antibody complex. The extent of covalent labelling was 0.5–0.9mol of hapten bound/mol of antibody and, by using an immunoadsorbent, ant...

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Dettagli Bibliografici
Autori principali: Fisher, Christopher E., Press, Elizabeth M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1974
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166260/
https://ncbi.nlm.nih.gov/pubmed/4219135
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