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Stimulation of ornithine decarboxylase activity and inhibition of S-adenosyl-l-methionine decarboxylase activity in leukaemic mice by methylglyoxal bis(guanylhydrazone) (Short Communication)

Administration of methylglyoxal bis(guanylhydrazone) to leukaemic mice results in an early depression followed by a marked elevation of S-adenosyl-l-methionine decarboxylase activity. Further, there is an early prolonged increase in the activity of ornithine decarboxylase, the initial enzyme in the...

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Bibliographic Details
Main Authors: Heby, Olle, Sauter, Sharon, Russell, Diane H.
Format: Artigo
Language:Inglês
Published: 1973
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166065/
https://ncbi.nlm.nih.gov/pubmed/4786532
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