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Effects of bis(guanylhydrazones) on the activity and expression of ornithine decarboxylase.

Derivatives of glyoxal bis(guanylhydrazone) (GBG), such as methylglyoxal bis(guanylhydrazone) and ethylglyoxal bis(guanylhydrazone), are potent inhibitors of S-adenosylmethionine decarboxylase (EC 4.1.1.50), the key enzyme required for the synthesis of spermidine and spermine. These compounds, but n...

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Dettagli Bibliografici
Autori principali: Nikula, P, Alhonen-Hongisto, L, Jänne, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1152727/
https://ncbi.nlm.nih.gov/pubmed/4062886
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