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Biochemical effects of the hypoglycaemic compound pent-4-enoic acid and related non-hypoglycaemic fatty acids. Effects of the free acids and their carnitine esters on coenzyme A-dependent oxidations in rat liver mitochondria

1. The synthesis of pent-4-enoyl-l-carnitine, cyclopropanecarbonyl-l-carnitine and cyclobutanecarbonyl-l-carnitine is described. 2. Pent-4-enoate strongly inhibits palmitoyl-l-carnitine oxidation in coupled but not in uncoupled mitochondria. Pent-4-enoyl-l-carnitine strongly inhibits palmitoyl-l-car...

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Hlavní autoři: Holland, P. C., Sherratt, H. S. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1973
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165935/
https://ncbi.nlm.nih.gov/pubmed/4772622
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