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Colchicine binding to bovine anterior pituitary slices and inhibition of growth-hormone release.

The uptake of [ring C-methoxyl-3H]colchicine into bovine anterior pituitary slices was studied. The data suggest that more than one site exists for the binding of colchicine. At low concentrations colchicine binds to saturable trypsin-sensitive site(s), with a dissociation constant of 3.1 +/- 0.69 m...

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Détails bibliographiques
Auteurs principaux: Sheterline, P, Schofield, J G, Mira, F
Format: Artigo
Langue:Inglês
Publié: 1975
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165563/
https://ncbi.nlm.nih.gov/pubmed/1200986
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