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Increase in pituitary adenosine 3′:5′-cyclic monophosphate content and potentiation of growth-hormone release from heifer anterior pituitary slices incubated in the presence of 3-isobutyl-1-methylxanthine

The release of growth hormone from heifer anterior pituitary slices and the cyclic AMP content of the slices were increased by the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine, both increases being related to inhibitor concentration over the range 0.1–1.0mm. Neither Ba(2+) (6.9 or 2.3mm),...

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Bibliographic Details
Main Authors: Schofield, J. George, McPherson, Margaret
Format: Artigo
Language:Inglês
Published: 1974
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168280/
https://ncbi.nlm.nih.gov/pubmed/4374194
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