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Initiation of DNA Replication within oriP Is Dispensable for Stable Replication of the Latent Epstein-Barr Virus Chromosome after Infection of Established Cell Lines

The 165-kb circularized chromosome of Epstein-Barr virus (EBV) is replicated in latently infected cells once per cell cycle by host proteins during S phase. Replication initiates at multiple sites on latent EBV chromosomes, including within a 1.8-kb region called oriP, which can provide both replica...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Norio, Paolo, Schildkraut, Carl L., Yates, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954558/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.18.8563-8574.2000
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