Mutants of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase Resistant to Nonnucleoside Reverse Transcriptase Inhibitors Demonstrate Altered Rates of RNase H Cleavage That Correlate with HIV-1 Replication Fitness in Cell Culture

Lignende værker

• Reduced Fitness in Cell Culture of HIV-1 with Nonnucleoside Reverse Transcriptase Inhibitor-Resistant Mutations Correlates with Relative Levels of Reverse Transcriptase Content and RNase H Activity in Virions
  af: Wang, Jiong, et al.
  Udgivet: (2010)
• Unique progressive cleavage mechanism of HIV reverse transcriptase RNase H
  af: Wisniewski, Michele, et al.
  Udgivet: (2000)
• Nonnucleoside Reverse Transcriptase Inhibitor-Resistant HIV Is Stimulated by Efavirenz during Early Stages of Infection
  af: Wang, Jiong, et al.
  Udgivet: (2011)
• Efavirenz Stimulates HIV-1 Reverse Transcriptase RNase H Activity by a Mechanism Involving Increased Substrate Binding and Secondary Cleavage Activity
  af: Muchiri, John M, et al.
  Udgivet: (2013)
• Nonnucleoside Reverse Transcriptase Inhibitor Hypersusceptibility and Resistance by Mutation of Residue 181 in HIV-1 Reverse Transcriptase
  af: Barnard, John P., et al.
  Udgivet: (2019)