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Design, synthesis and DNA-binding capacity of a new peptidic bifunctional intercalating agent.

A lysyl-lysine bifunctional derivative of 9-aminoacridine has been synthesized and its DNA-binding capacity established by electron-paramagnetic-resonance study. For this purpose the binding parameters of a spin-labelled aminoacridine probe were estimated and the affinities of the lysylacridinyl-lys...

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Bibliografiske detaljer
Main Authors: Bernier, J L, Henichart, J P, Catteau, J P
Format: Artigo
Sprog:Inglês
Udgivet: 1981
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1163401/
https://ncbi.nlm.nih.gov/pubmed/6280671
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