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Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(ii) macrocycle

An intercalator-linked macrocycle 3,6-bis(dimethylamino)-10-(6-[1,4,7-triazacyclononane]hexyl) acridinium bromide was synthesized, its copper(ii) complex was prepared, and the DNA cleavage activity of this metal complex was compared to that of the intercalator-free (Cu[9]aneN(3))(2+) complex.

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Tseng, Ta-Sheng Andrew, Burstyn, Judith N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989323/
https://ncbi.nlm.nih.gov/pubmed/19082122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b812183d
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