Evidence for the participation of calmodulin in stimulus–secretion coupling in the pancreatic β-cell

1. The ability of a range of phenothiazines to inhibit activation of brain phosphodiesterase by purified calmodulin was studied. Trifluoperazine, prochlorperazine and 8-hydroxyprochlorperazine produced equipotent dose-dependent inhibition with half-maximum inhibition at 12μm. When tested at 10 or 50...

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Main Authors: Gagliardino, Juan J., Harrison, Donna E., Christie, Michael R., Gagliardino, Elma E., Ashcroft, Stephen J. H.
Format: Artigo
Jezik:Inglês
Izdano: 1980
Teme:
Metabolism, Regulation and Control Processes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1162418/
https://ncbi.nlm.nih.gov/pubmed/6263264
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