Requirement for calcium ions in acetylcholine-stimulated phosphodiesteratic cleavage of phosphatidyl-myo-inositol 4,5-bisphosphate in rabbit iris smooth muscle

1. The mechanism of acetylcholine-stimulated breakdown of phosphatidyl-myo-inositol 4,5-bisphosphate and its dependence on extracellular Ca(2+) was investigated in the rabbit iris smooth muscle. 2. Acetylcholine (50μm) increased the breakdown of phosphatidylinositol bisphosphate in [(3)H]inositol-la...

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Bibliographic Details
Main Authors: Akhtar, Rashid A., Abdel-Latif, Ata A.
Format: Artigo
Language:Inglês
Published: 1980
Subjects:
Metabolism, Regulation and Control Processes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1162401/
https://ncbi.nlm.nih.gov/pubmed/6263262
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