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Requirement for calcium ions in acetylcholine-stimulated phosphodiesteratic cleavage of phosphatidyl-myo-inositol 4,5-bisphosphate in rabbit iris smooth muscle

1. The mechanism of acetylcholine-stimulated breakdown of phosphatidyl-myo-inositol 4,5-bisphosphate and its dependence on extracellular Ca(2+) was investigated in the rabbit iris smooth muscle. 2. Acetylcholine (50μm) increased the breakdown of phosphatidylinositol bisphosphate in [(3)H]inositol-la...

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Detalhes bibliográficos
Main Authors: Akhtar, Rashid A., Abdel-Latif, Ata A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1162401/
https://ncbi.nlm.nih.gov/pubmed/6263262
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