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The stimulus–secretion coupling of glucose-induced insulin release. Metabolism of glucose in K(+)-deprived islets

1. When pancreatic islets were exposed to a K(+)-free medium, the intracellular concentration of K(+) was decreased and that of Na(+) increased. 2. In the K(+)-deprived islets, the utilization of [5-(3)H]glucose, output of lactic acid and oxidation of [U-(14)C]-glucose were decreased by about 30–40%...

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Bibliographic Details
Main Authors: Sener, Abdullah, Kawazu, Shoji, Malaisse, Willy J.
Format: Artigo
Language:Inglês
Published: 1980
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1161518/
https://ncbi.nlm.nih.gov/pubmed/6989359
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