The stimulus-secretion coupling of glucose-induced insulin release. Effect of exogenous pyruvate on islet function.

1. In isolated pancreatic islets, pyruvate causes a shift to the left of the sigmoidal curve relating the rate of insulin release to the ambient glucose concentration. The magnitude of this effect is related to the concentration of pyruvate (5--90 mM) and, at a 30 mM concentration, is equivalent to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sener, A, Kawazu, S, Hutton, J C, Boschero, A C, Devis, G, Somers, G, Herchuelz, A, Malaisse, W J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1978
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186223/
https://ncbi.nlm.nih.gov/pubmed/365174
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