Induction of Hepatitis C Virus E1 Envelope Protein-Specific Immune Response Can Be Enhanced by Mutation of N-Glycosylation Sites

Deglycosylation of viral glycoproteins has been shown to influence the number of available epitopes and to modulate immune recognition of antigens. We investigated the role played by N-glycans in the immunogenicity of hepatitis C virus (HCV) E1 envelope glycoprotein, a naturally poor immunogen. Eigh...

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Vydáno v:	J Virol
Hlavní autoři:	Fournillier, A., Wychowski, C., Boucreux, D., Baumert, T. F., Meunier, J.-C., Jacobs, D., Muguet, S., Depla, E., Inchauspé, G.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2001
Témata:	Vaccines and Antiviral Agents
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116104/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11711599/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.24.12088-12097.2001
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