p53-Mediated Repression of Alpha-Fetoprotein Gene Expression by Specific DNA Binding

Aberrant expression of the alpha-fetoprotein (AFP) gene is characteristic of a majority of hepatocellular carcinoma cases and serves as a diagnostic tumor-specific marker. By dissecting regulatory mechanisms through electromobility gel shift, transient-transfection, Western blot, and in vitro transc...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lee, Kathleen C., Crowe, Alison J., Barton, Michelle Craig
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116057/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9891062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.2.1279
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