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p53-Mediated Repression of Alpha-Fetoprotein Gene Expression by Specific DNA Binding

Aberrant expression of the alpha-fetoprotein (AFP) gene is characteristic of a majority of hepatocellular carcinoma cases and serves as a diagnostic tumor-specific marker. By dissecting regulatory mechanisms through electromobility gel shift, transient-transfection, Western blot, and in vitro transc...

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Udgivet i:Mol Cell Biol
Principais autores: Lee, Kathleen C., Crowe, Alison J., Barton, Michelle Craig
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116057/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9891062/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.2.1279
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