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Local Secretory Immunoglobulin A and Postimmunization Gastritis Correlate with Protection against Helicobacter pylori Infection after Oral Vaccination of Mice

C57BL/6 mice were orally immunized with five weekly doses of 2 mg, 200 μg, or 2 μg of Helicobacter pylori (Sydney strain) whole-cell sonicate combined with cholera toxin. One week after the last vaccination, mice were challenged with 5 × 10(7) CFU of live H. pylori three times at 2-day intervals. At...

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Библиографические подробности
Главные авторы: Goto, Takayuki, Nishizono, Akira, Fujioka, Toshio, Ikewaki, Junko, Mifune, Kumato, Nasu, Masaru
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 1999
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC116000/
https://ncbi.nlm.nih.gov/pubmed/10225917
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