Local Secretory Immunoglobulin A and Postimmunization Gastritis Correlate with Protection against Helicobacter pylori Infection after Oral Vaccination of Mice

C57BL/6 mice were orally immunized with five weekly doses of 2 mg, 200 μg, or 2 μg of Helicobacter pylori (Sydney strain) whole-cell sonicate combined with cholera toxin. One week after the last vaccination, mice were challenged with 5 × 10(7) CFU of live H. pylori three times at 2-day intervals. At...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Goto, Takayuki, Nishizono, Akira, Fujioka, Toshio, Ikewaki, Junko, Mifune, Kumato, Nasu, Masaru
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116000/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10225917/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.5.2531-2539.1999
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