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Gating charge and ionic currents associated with quinidine block of human Kv1.5 delayed rectifier channels.
1. The mechanism of quinidine-induced ionic and gating current inhibition was studied in human Kv1.5 (hKv1.5) delayed rectifier channels expressed in human embryonic kidney cells. In the steady state, quinidine produced a voltage-dependent block between +30 and +120 mV (Kd at +60 mV = 7.2 microM) wi...
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| Glavni autor: | |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1997
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1159285/ https://ncbi.nlm.nih.gov/pubmed/9130163 |
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