TRADD Domain of Epstein-Barr Virus Transforming Protein LMP1 Is Essential for Inducing Immortalization and Suppressing Senescence of Primary Rodent Fibroblasts

Mutation analysis of latent membrane protein 1 (LMP1) in Epstein-Barr virus (EBV)-induced B-cell immortalization revealed two transformation effector sites, TES1 and TES2. TES2 mediates the interaction with tumor necrosis factor receptor-associated death domain protein (TRADD) and plays a key role i...

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Pubblicato in:	J Virol
Autori principali:	Xin, Baozhong, He, Zhimin, Yang, Xinhai, Chan, Ching-Ping, Ng, Mun-Hon, Cao, Liang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Transformation and Oncogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115928/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11222727/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.6.3010-3015.2001
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