TRADD Domain of Epstein-Barr Virus Transforming Protein LMP1 Is Essential for Inducing Immortalization and Suppressing Senescence of Primary Rodent Fibroblasts

Mutation analysis of latent membrane protein 1 (LMP1) in Epstein-Barr virus (EBV)-induced B-cell immortalization revealed two transformation effector sites, TES1 and TES2. TES2 mediates the interaction with tumor necrosis factor receptor-associated death domain protein (TRADD) and plays a key role i...

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Detalhes bibliográficos
Main Authors: Xin, Baozhong, He, Zhimin, Yang, Xinhai, Chan, Ching-Ping, Ng, Mun-Hon, Cao, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115928/
https://ncbi.nlm.nih.gov/pubmed/11222727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.6.3010-3015.2001
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