The Ews-ERG Fusion Protein Can Initiate Neoplasia from Lineage-Committed Haematopoietic Cells

The EWS-ERG fusion protein is found in human sarcomas with the chromosomal translocation t(21;22)(q22;q12), where the translocation is considered to be an initiating event in sarcoma formation within uncommitted mesenchymal cells, probably long-lived progenitors capable of self renewal. The fusion p...

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Autores principales: Codrington, Rosalind, Pannell, Richard, Forster, Alan, Drynan, Lesley F, Daser, Angelika, Lobato, Nati, Metzler, Markus, Rabbitts, Terence H
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2005
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1159166/
https://ncbi.nlm.nih.gov/pubmed/15974803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030242
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