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Random, Asynchronous, and Asymmetric Transcriptional Activity of Enhancer-Flanking Major Immediate-Early Genes ie1/3 and ie2 during Murine Cytomegalovirus Latency in the Lungs

The lungs are a major organ site of cytomegalovirus (CMV) pathogenesis, latency, and recurrence. Previous work on murine CMV latency has documented a high load and an even distribution of viral genomes in the lungs after the resolution of productive infection. Initiation of the productive cycle requ...

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Detalhes bibliográficos
Main Authors: Grzimek, Natascha K. A., Dreis, Doris, Schmalz, Susanne, Reddehase, Matthias J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115894/
https://ncbi.nlm.nih.gov/pubmed/11222693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.6.2692-2705.2001
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