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Patchwork Pattern of Transcriptional Reactivation in the Lungs Indicates Sequential Checkpoints in the Transition from Murine Cytomegalovirus Latency to Recurrence

The lungs are a significant organ site of murine cytomegalovirus (mCMV) latency. We have shown that activity of the major immediate-early promoter (MIEP), which drives the transcription from the ie1-ie3 transcription unit, does not inevitably initiate the productive cycle (S. K. Kurz, M. Rapp, H.-P....

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Kurz, Sabine K., Reddehase, Matthias J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112881/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482614/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8612-8622.1999
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