Role for Human Immunodeficiency Virus Type 1 Tat Protein in Suppression of Viral Reverse Transcriptase Activity during Late Stages of Viral Replication

We have examined the role of the human immunodeficiency virus type 1 (HIV-1) Tat protein in the regulation of reverse transcription. We show that a two-exon but not a one-exon form of Tat markedly suppressed cell-free reverse transcriptase (RT) activity. Conversely, viruses expressing two-exon Tat (...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kameoka, Masanori, Rong, Liwei, Götte, Matthias, Liang, Chen, Russell, Rodney S., Wainberg, Mark A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115892/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11222691/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.6.2675-2683.2001
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