A unique P-region residue is required for slow voltage-dependent gating of a G protein-activated inward rectifier K+ channel expressed in Xenopus oocytes.

1. The structural determinants of a G protein-activated inwardly rectifying potassium channel, GIRK1 (KIR3.1), involved in voltage- and time-dependent gating properties were investigated by heterologous expression of chimeric constructs and point mutants in Xenopus oocytes. 2. Chimeras between GIRK1...

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Bibliographic Details
Main Authors: Kofuji, P, Doupnik, C A, Davidson, N, Lester, H A
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1158702/
https://ncbi.nlm.nih.gov/pubmed/8683463
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